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BE Seminar: “Where Do Therapeutic Antibodies Go?: A First-In-Human Journey” (Guolan Lu, Stanford)
February 15 @ 3:30 PM - 4:30 PM
Guolan Lu
Instructor, Otolaryngology (Head and Neck Surgery), Stanford University
Dr. Lu is an instructor in Dr. Garry Nolan’s lab at Stanford University and a recipient of an NIH K99/R00 Pathway to Independence Award from the National Cancer Institute. Dr. Lu is a biomedical engineer who conducts translational research at the interface of biomedical imaging, artificial intelligence, and spatial omics to advance next-generation cancer theragnostics. Dr. Lu received her Ph.D. from the joint Biomedical Engineering Department of Georgia Tech and Emory University.
Research Synopsis:
Dr. Lu will introduce a fluorescence molecular imaging method to track therapeutic antibody delivery from cancer patients in vivo, down to single cells, through first-in-human clinical trials. She will present a new experimental and AI-powered analytical framework that integrates single-cell drug imaging with spatial omics to decipher drug-target-microenvironment in situ. This work establishes a foundational framework for studying drug pharmacology in the context of tissue biology in serious diseases including cancer, autoimmunity, and chronic inflammation.