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Escaping the Endosome: BEND Lipids Improve LNP mRNA Delivery and Gene Editing

Check out this article highlighting Mitchell Lab postdoc Marshall Padilla's research on the design of a new class of lipids called branched endosomal disruptor (BEND) lipids that improve LNP delivery of mRNA and gene-editing tools.

  • Louisa SpinnerByLouisa Spinner
  • OnMarch 24, 2025
  • News

Spaces That Spark Discovery: A Look Inside One uCity Square

Check out this article highlighting the exceptional lab space at the Center for Precision Engineering for Health located at One uCity Square!

  • Louisa SpinnerByLouisa Spinner
  • OnMarch 24, 2025
  • News

Penn Engineering Today: Inaugural CPE4H Symposium Explores Engineering’s Role in Precision Medicine

On November 8, CPE4H hosted its first inaugural symposium, which showcased current innovative work from the members of the Center at Penn, and also research from scientists at The University of Washington, Duke University and Northwestern University.

  • Marian BechtelByMarian Bechtel
  • OnJanuary 17, 2025
  • Chemical and Biomolecular EngineeringSeminar

CBE Seminar: “Scalable Access to the Hidden Topologies of Biology” (Albert Keung, North Carolina State University)

Albert Keung Associate Professor, North Carolina State University The Keung group engineers cellular and molecular…

  • Marian BechtelByMarian Bechtel
  • OnOctober 8, 2024
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Posts

Engineering a Healthier Heart: Noor Momin Receives AHA Transformational Project Award (Penn Bioengineering Blog)

July 18, 2025

Penn Today: Bioengineers on the brink of breaching blood-brain barrier

February 7, 2024

Penn Engineering Today: Inaugural CPE4H Symposium Explores Engineering’s Role in Precision Medicine

January 17, 2025

Spaces That Spark Discovery: A Look Inside One uCity Square

March 24, 2025

Escaping the Endosome: BEND Lipids Improve LNP mRNA Delivery and Gene Editing

March 24, 2025

"We're looking at a potentially universal approach to making cellular therapies safer for all patients."

Michael Mitchell

Contact

  • Email: cpe4h@seas.upenn.edu

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University of Pennsylvania